A Review on Green Synthesis of Carbon Nanoparticles and its Biomedical and Wound Healing Applications
Steffy Dominic, Perumal Elumalai, Rajeshkumar Shanmugam
Carbon Nanoparticle (CNPs) shows significant impact in biomedical fields, especially in targeted drug delivery system, cancer therapies and wound healing applications. Green synthesis‖ of carbon-based nanoparticle from bio-waste fruit peels, leaves, presents eco- friendly, low cost, high scalability than other chemical and physical method. This review aims to highlights the green synthesis of carbon nanoparticle through various methods, including hydrothermal, microwave assisted, ultrasonification, pyrolysis, hydrothermal and chemical oxidation, chemical vapor oxidation (CVD), Arc discharge, laser ablation, electrospinning, template assisted growth, freeze drying and highlights major forms of carbon nanoparticles such as Carbon Dots (CDs), Carbon Nanotubes (CNTs), Carbon Nanosphere (CNs), Mesoporouscarbon Nanoparticle (MCNs), and Nanodiamonds (NDs) and its biomedical applications. This review focus on role of carbon nanoparticle on wound healing and carbon nanoparticle enhances on collagen deposition, accelerates hemostasis and tissue regeneration. By incorporating both the green synthesis and its biomedical applications emerging the direction for the potent wound healing applications in eco-friendly methods.